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Lu, 28 years from Hongkong
Lu's ALEX³ test results
Allergen source
Allergen
Biochemical designation
IgE Level [kUA/L]
D. farinae
Der f 2
NPC2
2.45
D. pteronyssinus
Der p 2
NPC2
3.10
D. pteronyssinus
Der p 10
Tropomyosin
5.87
Blomia tropicalis
Blo t 10
Tropomyosin
3.02
Tyrophagus putrescentiae
Tyr p 10
Tropomyosin
2.67
American cockroach
Per a 7
Tropomyosin
3.83
Allergen source
Allergen
Biochemical designation
IgE Level [kUA/L]
Anisakis simplex
Ani s 3
Tropomyosin
1.82
Crab mix
Chi spp.
Extract
0.95
Lobster
Hom g
Extract
0.58
Shrimp
Pen m 1
Tropomyosin
4.01
Shrimp mix
Lit spp.
Extract
0.98
Giant freshwater prawn
Mac r 1
Tropomyosin
3.78
Northern prawn
Pan b
Extract
1.01
Squid
Lol spp.
Extract
0.48
Venus clam
Rud spp.
Extract
0.31
Analysis
House dust mites
- Der p 2, Der f 2: major HDM allergens: house dust mite allergy
- Der p 10 is a highly cross-reactive tropomyosin
Seafood
- Pen m 1 from shrimp is a risk marker for severe seafood allergy
Summary
- Lu’s mite allergy (tropomyosin sensitisation, Der p 10) leads to clinically relevant cross-reactions to seafood
- Mite encasing, AIT against house dust mite and avoidance of seafood is advised
- An emergency set could be prescribed, as seafood can cause severe allergic reactions
Novel findings revealed by ALEX³
- Tropomyosin syndrome
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