DE
EN
ES
Ayleen, 16 years from China
Ayleen's ALEX³ test results
Allergen source
Allergen
Biochemical designation
IgE Level [kUA/L]
Malassezia sympodialis
Mala s 5
Unknown
36.93
Malassezia sympodialis
Mala s 6
Cyclophilin
4.61
Malassezia sympodialis
Mala s 11
Mn Superoxid-Dismutase
35.00
Aspergillus fumigatus
Asp f 6
Mn Superoxid-Dismutase
18.73
Analysis
Malassezia sympodialis
- Sensitisation to Malassezia sympodialis was detected
- Mala s 11 is able to induce autoreactive T cells: plays an important role in atopic dermatitis
Aspergillus fumigatus
- Sensitisation to spores of Aspergillus fumigatus was found that can cause allergic symptom like rhinoconjunctivitis or allergic asthma
Summary
- Patient suffers from Malassezia allergy
- Malassezia sympodialis is a yeast fungus commonly found in patients with atopic dermatitis
- Especially seborrhoeic skin areas (e.g., head, neck) are preferred habitats
- Consistent skin care is the basis of AD therapy
- In case of skin inflammation in AD episodes, anti-inflammatory treatment is necessary
- AD patients may benefit from antifungal therapy
- Due to the strong cross-reactivity of Mn-superoxide dismutases, sensitisation to Aspergillus fumigatus could also be detected – but as Ayleen has no respiratory symptoms, therapy does not have to be considered
Novel findings revealed by ALEX³
- Sensitised to Malassezia sympodialis & Aspergillus fumigatus
)
)